Research

Our research is conducted in the broad field of human physiology with the main focus on the brain and mind. Brain and mind research being a multidisciplinary and integral area is central in many biological and medical studies.

Our main areas of focus and expertise are:

  • Brain Research (focusing on EEG, MEG)
  • Systemic Psychophysiology / Neurological and Psychiatric Disorders
  • Developmental Neuropsychology
  • Twin and Multiples Psychobiology
  • Development and testing of new scientific tools or instruments and Psycho-Pharmacology studies


    Ongoing main projects:

  • Development of advanced methods for qEEG/MEG analysis which:
    1. are sensitive to temporal structure of the signal,
    2. do not require prior knowledge of the underlying dynamics,
    3. do not contain averaging procedures,
    4. have special tests for non-random and non-occasional nature of the results,
    5. produce results which are ease to interpret in terms of their neurophysiological correlates
  • Advanced EEG-guided personalised TMS treatment of depression
  • EEG studies of patients in vegetative (VS) and minimally conscious states (MCS)
  • EEG study of dream phenomenology
  • Development of Operational Architectonics framework of brain and mind functioning
  • Isomorphism between EEG/MEG microstructure and a structure of phenomenal experience (consciousness)
  • Application of Operational Architectonics framework of brain-mind functioning to self-organizing dynamic distributed computational systems

    Earlier completed main projects:

    Since 2002:

    Electrophysiologic mechanisms of working memory

    2002 - 2003

    Dynamic processes in electromagnetic brain activity during multisensory perception and cognition

    2003 - 2005

    Microstructural analysis of electromagnetic brain signals under psychopharmacological influence

    2005 - 2006

    Advanced analysis of electrical brain activity in un-medicated naïve out-patients with major depressive disorder (MDD)

    2005 - 2006

    Characterization of pure hypnotic state without hallucinations, as altered states of consciousness, using advanced analysis of electrical brain activity

    2005 - 2006

    Epileptic brain as physiologic adaptation: Microstructural analysis of electromagnetic brain signals

    2006 - 2008

    The influence of chronic opioid addiction on the spatio-temporal structure of the electrical brain signal (longitudinal study)

    2010 - 2012

    Development of differentiation index distinguishing Vegetative and Minimally Conscious States in brain-damaged noncommunicative patients (longitudinal study), Phase I.


    Main collaborative research partners:

  • Dr. Giuseppe Galardi (MD),Dr. Sergio Bagnato (MD, PhD) and Dr. Cristina Boccagni (MD) , The Foundation Institute San Raffaele - G. Giglio (FISRG), ITALY
  • Dr. Murat Özgören (MD,PhD), Dept. of Biophysics, Faculty of Medicine, Dokuz Eylul University (DEU), TURKEY
  • Eugene Burmakin, Nokia Siemens Networks, Espoo. FINLAND
  • BioMag Laboratory, Medical Engineering Centre, Helsinki University Central Hospital. FINLAND
  • The Consciousness Research Group, Department of Philosophy, University of Turku, Center for Cognitive Neuroscience. FINLAND.
  • Dr. Giorgio Marchetti and Dr. Giulio Benedetti, Mind, Consciousness, and Language Network , ITALY
  • Dr. Tarja Kallio-Tamminen, Physics Foundations Society and Society for Natural Philosophy. FINLAND


    The co-heads of research team are:

    Dr Andrew A. Fingelkurts

    Dr Alexander A. Fingelkurts

    Drs. Andrew A. and Alexander A. Fingelkurts have careers in academic neuroscience, psychophysiology and clinical research, with a considerable number of publications in scientific journals, book chapters and a lecturing practice in areas of neuroscience and applied psychophysiology.

    Their areas of expertise include neuroinformatics, quantitative EEG diagnostics, advanced methods of EEG/MEG analysis and systemic psychophysiology. They have been consultants to the Medico-diagnostic Center of Armed Forces General Staff of Russian Federation through the Moscow State University, and the consultants to the neurological division of the Medical Centre of Russian Federation President's Management Department, served as researchers of the State Scientific Centre of Russian Federation - Institute for Biomedical Problems, and as senior researchers at the Research Centre for Computational Science and Engineering in Laboratory of Computational Engineering Cognitive Science and Technology at Helsinki University of Technology and at the BioMag Laboratory, Medical Engineering Centre, of Helsinki University Central Hospital. Drs. Fingelkurts are members of Neuroinformatics Organization (NIO, since 2002), Organization of Human Brain Mapping (OHBM, since 1999), New York Academy of Sciences (NYAS, since 1997), and International Brain Research Organization (IBRO, since 1994).

    Drs. Fingelkurts entered the field of identification of reproducible and stable spatial-temporal relations between segments of activity in electroencephalogram (EEG) and functional brain states in 1998, with doctoral dissertations concerned with EEG segmentation. Subsequently, in a sizeable number of independent studies Drs. Fingelkurts generated a large number of observations under a variety of conditions that identified meaningful manifestations in the EEG, having the form of rapid transitional processes interspersed between piecewise stationary records. On the basis of this work, they formulated a framework of "Operational Architectonics (OA) of Brain-Mind Functioning" which is based on the joint analysis of cognitive and electromagnetic data (EEG and MEG). According to OA every conscious phenomenon is brought to existence by the joint operations of many functional and transient neuronal assemblies in the brain. Further, the functioning of the brain is always operational (made up of operations), and its structure is characterized by a hierarchy of operations of increasing complexity: from single neurons to synchronized neuronal assemblies. In a number of publications Drs. Fingelkurts clearly identified interesting relations between mental states and the EEG patterns uncovered by the method of Operational Synchrony which delineates cooperative neural interactions at a functionally relevant level of neuronal organization.

    The work of brothers Fingelkurts represents a bold attempt to apply insight from both neuroscience and physics to the phenomenon of consciousness. They delve into the physics of consciousness by considering the nature of space and time within the conscious mind. This leads them to the notion of an operational space-time generated by synchronized neural activity (as evidenced by EEG, – one of the best-documented correlates of consciousness) which, they proposed, is isomorphic to the phenomenological space-time of subjective perceptions. Drs. Fingelkurts then consider a mind-brain hierarchy consisting of nested increasingly coordinated mental operations taking place within their operational space-time from relatively isolated unconscious events become increasingly integrated and involving more and more of the brain’s activity until, at its highest level, it equates with unified conscious perceptual experience.